Advanced kidney disease may be linked to cognitive impairment

Markers of chronic kidney disease severity could be predictive of cognitive impairment.

In a study published in JAMA Network Open, investigators asked more than 5,600 patients with chronic kidney disease to undergo cognitive assessments.

After a median follow-up of six years, the investigators found that the patients with a higher urinary protein to creatinine ratio were more likely to experience impairments in attention and processing speed as well as executive function. Those with both greater urinary protein to creatinine ratio and a lower estimated glomerular filtration rate had higher rates of global cognition impairments.

The findings suggested that worsening chronic kidney disease could be a risk factor for cognitive decline.

Read more: JAMA Network Open

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