Ankylosing spondylitis may have a causal relationship with heart failure

Investigators may have uncovered the link between ankylosing spondylitis and heart failure.

Ankylosing spondylitis is a type of arthritis characterized by inflammation in the joints and ligaments of the spine.

In a study, published in Frontiers in Genetics, the investigators used genome-wide association studies to explore the causal relationship between ankylosing spondylitis and cardiovascular diseases — including heart failure, atrial fibrillation, coronary artery disease, ischemic stroke, myocardial infarction and valvular heart disease.

The data included in the study demonstrated an association between ankylosing spondylitis and an increased risk of heart failure; however, there were no causal relationships identified between ankylosing spondylitis and other cardiovascular diseases.

The investigators concluded that further research is needed to confirm their findings and better understand the mechanisms behind the causal relationship between the diseases.

Read more: Frontiers in Genetics

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