Antibiotic therapy in back pain

Researchers examined the safety and efficacy of antibiotic treatment in reducing chronic low back pain.

In a study published in JAMA Network Open, the researchers randomly assigned 170 patients aged 18 to 60 years with chronic low back pain with MRI-confirmed disc herniation to receive either 500/125 milligrams of amoxicillin-clavulanate or placebo for a period of about three months.

After a follow-up of 12 months, the researchers found no statistically significant differences in pain intensity between amoxicillin-clavulanate and placebo. The findings indicated that clinicians should avoid managing chronic low back pain with disc herniation with antibiotic therapy.

Read more: JAMA Network Open

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