At-home treatment may be effective in Alzheimer’s disease
A novel, home-based treatment approach could help improve clinical outcomes in patients with Alzheimer’s disease.
In a study published in JAMA Network Open, researchers randomly assigned 50 patients with prodromal or mild Alzheimer’s disease to receive at-home gamma-transcranial alternating current stimulation over the precuneus or a sham simulation for a period of eight weeks followed by an eight-week open-label phase in which all of the patients received at-home gamma-transcranial alternating current stimulation.
The researchers discovered that at-home gamma-transcranial alternating current stimulation was effective in entraining gamma rhythms over the parietal and frontal regions of the brain. Further, at-home gamma-transcranial alternating current stimulation was effective in improving global cognitive functions, activities of daily living, associative memory performance and cholinergic transmission compared with the sham simulation. The treatment was also found to be safe.
The findings represent the feasibility and potential of the novel, noninvasive technique to enhance clinical outcomes in this patient population.
Read more: JAMA Network Open
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