Avoiding common transplant complication

A preclinical study in mice could help illuminate strategies for improving the success rate of liver transplantation.

Some patients experience ischemia-reperfusion injury followed by graft dysfunction and subsequent liver failure when the restoration of blood supply to the donor liver triggers damage-inducing inflammation, according to a news report from Reuters. However, in the study published in JCI Insight, researchers uncovered that two proteins — CEACAM1 and HuR — can offer protective effects on the donor liver to prevent ischemia-reperfusion injury and minimize stress on the organ following transplantation.

The researchers hope their findings can help tackle current shortages in the number of viable organs for transplantation.

Read more: Reuters

The article presented here is intended to inform you about the broader media perspective on dentistry, regardless of its alignment with the ADA's stance. It is important to note that publication of an article does not imply the ADA's endorsement, agreement, or promotion of its content.