Cardiovascular-kidney-metabolic syndrome staging: Applying heart association framework to younger adults

Investigators have examined the relationship between early arterial injury and cardiovascular-kidney-metabolic syndrome.

In a study published in Circulation: Population Health and Outcomes, investigators assessed the cardiovascular-kidney-metabolic syndrome staging, Life’s Essential 8 scores defined by the American Heart Association, and carotid ultrasonography measures among nearly 1,300 young adult patients with a mean age of about 23 years.

The investigators found that about 21% of the participants were classified as having Stage 0 disease, whereas 40% of the participants had Stage 1 disease, 36% had Stage 2 disease and 3% had Stage 3 disease — characterized by excess adiposity, metabolic risk factors, and subclinical cardiovascular or advanced renal disease, respectively. They noted that the participants who exhibited stages 1 to 3 were more likely to have lower Life’s Essential 8 scores, greater mean-mean and mean-maximum carotid intima-medial thickness, and decreased gray-scale median.

The findings may improve the understanding of the correlation between early arterial injury and more advanced stages of cardiovascular-kidney-metabolic syndrome. The investigators hope their research can help inspire the development of preventive interventions in at-risk patients.

Read more: Circulation: Population Health and Outcomes

The article presented here is intended to inform you about the broader media perspective on dentistry, regardless of its alignment with the ADA's stance. It is important to note that publication of an article does not imply the ADA's endorsement, agreement, or promotion of its content.