Cardiovascular sequelae in patients with long COVID
Long COVID could be a risk factor for adverse cardiovascular effects in nonhospitalized patients.
In a study published in eClinicalMedicine, investigators used data from the MIRACLE-S cohort to examine adverse cardiovascular outcomes — including myocardial infarction, heart failure, cardiac arrhythmias, stroke and peripheral artery disease — in more than 1.2 million individuals without long COVID and patients aged 18 to 65 years whose clinicians diagnosed them with long COVID between October 2020 and January 2025. They excluded individuals who had been hospitalized with severe COVID-19 infections and those with preexisting cardiovascular disease.
The investigators identified nearly 9,000 cases of long COVID among the cohort. Compared with controls, the patients with long COVID were more likely to experience cardiac arrhythmia, coronary artery disease and the composite cardiovascular outcome. Female patients with long COVID also had an elevated risk of heart failure and peripheral artery disease.
As a result of the findings, the investigators urged clinicians to conduct systematic follow-up to assess the risk of incident cardiovascular disease among patients with long COVID.
Read more: eClinicalMedicine
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