Diabetes risk factors identified

A novel risk stratification strategy could accurately predict the 10-year risk of diabetes.

In a study published in JAMA Network Open, investigators used data from the Rochester Epidemiology Project to examine diabetes risk factors among 44,992 individuals who received two or more fasting plasma glucose measurements from 2005 to 2017.

After a median follow-up of 6.8 years, the investigators noted that 8.6% of the participants developed diabetes. The 10-year cumulative risk of incident diabetes was 12.8%. All initial fasting plasma glucose levels outside of the 80 to 94 milligrams per deciliter range were indicative of a greater risk of diabetes. Both low and elevated levels predicted future diabetes development.

Using the factors of fasting plasma glucose levels, body mass index, age and sex, the investigators were able to accurately predict diabetes. For instance, participants with a higher BMI, those with a greater fasting plasma glucose levels, male participants and those aged 60 years and older had an increased the risk of developing diabetes.

The investigators hope their findings can provide clinicians with a tool to identify which patients may have the highest risk of developing diabetes and facilitate lifestyle and pharmacologic interventions to mitigate disease risk.

Read more: JAMA Network Open

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