Does cognition signal future depression?
Investigators examined whether cognitive impairments could help predict the risk of depression.
In a study published in BMJ Mental Health, the investigators used data from the UK Biobank to analyze the relationship between cognitive performance and the risk of first-incidence of depression or relapse among more than 3,700 participants with or without a history of depression.
The investigators found that the participants who had depression in remission had more than double the risk of future depression compared with those without a history of depression. Those without a depression history also showed a negative correlation between composite cognitive performance scores and the future risk of depression; however, the participants with depression in remission showed a positive correlation between composite cognitive performance scores and future depression risk. Neuroimaging with MRI offered limited findings.
The investigators concluded that lower baseline cognition could be linked to higher risks of future depression among those without a history of the condition. They emphasized that higher cognitive performance could predict the likelihood of future depression reporting among those with a history of depression.
Read more: BMJ Mental Health
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