Effect of climate on Botulinum toxin A dosing

Tailoring Botulinum toxin A treatment strategies to patients based on the type of climate they live in may improve their satisfaction and outcome.

In the study, published in Plastic and Reconstructive Surgery, the investigators analyzed the outcomes of 292 patients who resided in areas with high sun exposure and 231 patients who resided in areas with low sun exposure — both of which were treated with Botulinum toxin A injections for cosmetic purposes. They sought to better understand the effects of climate conditions on real-world dosing requirements.

The investigators discovered that the mean total dose of Botulinum toxin A injection was notably higher among the patients who experienced high sun exposure compared with those who experienced low sun exposure. Over 50% of the patients needed additional doses to achieve effective glabellar paralysis.

The investigators called for treatment protocols adapted to climate conditions to ensure more consistent results in this patient population.

Read more: Plastic and Reconstructive Surgery

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