Exploring benefits of gastric bypass in patients with severe obesity

A procedure known as Roux-en-Y gastric bypass may help reduce major atherogenic blood lipids and the risk of cardiovascular disease, according to study published in JAMA Surgery.

In the study, researchers assigned 78 patients with severe obesity to undergo either a very low-energy diet following Roux-en-Y gastric bypass surgery or a very low-energy diet alone for six weeks. Both of the patients subsequently followed a low-energy diet for three weeks.

Compared with those who received the very low-energy diet alone, the patients who underwent a combination of the diet and Roux-en-Y gastric bypass surgery experienced greater reductions in their low-density lipoprotein cholesterol, non-high-density lipoprotein cholesterol, apolipoprotein B and lipoprotein(a) levels. There were no statistically significant differences in glycemic control and blood pressure between the two groups.

The researchers concluded that the addition of Roux-en-Y gastric bypass surgery may provide cardiovascular benefits in patients with severe obesity independent of following a very low-energy diet.

Read more: JAMA Surgery

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