Gut microbiome could predict cardiovascular disease risk

Researchers may have uncovered a link between certain gut microbiota and the risk of coronary artery disease.

In a study published in mSystems, the researchers used fecal metagenomic shotgun sequencing to examine gut microbiota signatures among 42 patients with or without coronary artery disease.

The researchers identified 15 types of bacteria whose abundance or depletion was associated with coronary artery disease — including CAG-303 sp000437755, AM51-8 sp003478275, Ventrimonas sp900538475, UBA644 sp900547165, Slackia isoflavoniconvertens, Faecalibacterium prausnitzii, Catenibacterium sp000437715, Prevotella copri, Lachnospira eligens A and Holdemanella porci.

The findings indicated that alterations in gut-mediated inflammation and metabolic pathways could contribute to a heightened risk of coronary artery disease. The researchers hope the results of their study can lead to the development of novel therapeutics to mitigate the risk of cardiovascular disease.

Read more: mSystems

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