Insights into twin fetal development

Twin fetuses may accumulate fat tissue differently compared with singletons.

In a study published in JAMA Pediatrics, investigators used 2009 and 2013 ultrasound data to examine the fetal development of more than 300 twins and 2,500 singletons. They measured fetal abdominal area, maximum abdominal subcutaneous tissue thickness, fractional thigh volume as well as lean and fat thigh components.

The investigators discovered that twin fetuses had lower measurements for mean fractional thigh volume and abdominal areas compared with singleton fetuses. Fat accumulation was consistently lower as early as 15 weeks’ gestation, representing a potential evolutionary adaptation rather than a pathologic growth restriction.

The findings could advance the understanding of twin fetal development. However, more studies are needed to better examine growth patterns.

Read more: JAMA Pediatrics

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