Minimizing risk of dementia with prolonged NSAID use
The long-term use of nonsteroidal anti-inflammatory drugs could help reduce the risk of dementia.
In a study published in the Journal of the American Geriatrics Society, investigators used pharmacy dispensing records to examine the outcomes of less than 12,000 participants who didn’t have dementia.
After a follow-up of 14.5 years, the investigators found that compared with those who didn’t use NSAIDs, the participants who used NSAIDs over a period of greater than 24 months had a 12% decreased likelihood of developing dementia. However, use of NSAIDs for less than 24 months correlated with a slight increased risk of developing dementia.
Although the findings demonstrated the potential of NSAIDs for dementia prevention, the investigators didn’t recommend long-term use of the drugs because of their known adverse effects.
Read more: American Journal of the American Geriatrics Society
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