Oral frostbite case underscores risks of recreational nitrous oxide use

A recent case published in the New England Journal of Medicine is drawing attention to the risks of recreational nitrous oxide use, following an unusual instance of oral frostbite in a 23-year-old man. The patient experienced painful swallowing and hoarseness after inhaling the gas from a hand-held canister. Examination revealed damage to the soft palate and vocal cords, including ulceration and swelling. He was treated with pain relievers and topical medications but did not return for follow-up, according to MedPageToday.

Nitrous oxide, commonly known as “whippets” or “laughing gas,” is legally sold in small canisters often used in whipped cream dispensers. When released, the gas is extremely cold and can cause frostbite injuries, particularly to the mouth, hands and legs. These types of injuries are rare, with about 100 cases reported annually, but experts warn usage is on the rise.

The gas produces pain-relieving and mood-altering effects, including dissociation and hallucinations, by interacting with mood and opioid receptors. Experts say stress and easy access have contributed to its growing popularity, particularly during the COVID-19 pandemic. Health officials urge stronger regulation, warning of serious long-term effects like vitamin B12 deficiency and neurological damage. 

Read more: MedPageToday

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