Oral health’s role in systemic disease, cancer outcomes

Emerging evidence highlights the strong link between oral health and systemic conditions, including cancer, according to an article in The Lancet Regional Health Southeast Asia. Good oral hygiene — characterized by regular dental visits, tooth retention, and daily brushing — has been associated with reduced risk and improved prognosis of head and neck cancers.

Radiotherapy alters the oral microbiome, heightening the risk of complications, especially in those with periodontal disease. Regular dental visits are linked to reduced cancer mortality, particularly in oral cancers. However, data from southeast Asia on this association remain scarce, according to the article. Innovative diagnostics like activated matrix metalloproteinase-8 (aMMP-8)-based mouthrinse tests show promise for early detection of periodontal disease. 

The article noted that public health efforts, such as supervised toothbrushing programs in schools, have proven cost-effective in improving oral health and reducing inequalities. Challenges persist, including low prioritization of oral health and economic barriers. Integrating oral health into broader health care and educational settings — alongside tobacco cessation and policy reforms — can enhance cancer outcomes and overall health, especially in resource-limited regions like the southeast Asia region, according to the article. 

Read more: The Lancet Regional Health Southeast Asia 

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