Prevalence of chronic rhinosinusitis among men, women

Biological sex could determine the risk of chronic rhinosinusitis with or without nasal polyps.

In a cross-sectional study published in JAMA Otolaryngology-Head & Neck Surgery, investigators used the All of Us Research Program database to examine the relationship between biological sex, chronic rhinosinusitis diagnosis and disease biomarkers among a group of more than 250,000 participants.

The investigators found that compared with male sex, female sex was linked to a greater risk of being diagnosed with chronic rhinosinusitis without — but not with — nasal polyps as well as decreased concentrations of serum eosinophils. Female participants who had chronic rhinosinusitis without nasal polyps had lower immunoglobulin E levels compared with male participants with the condition.

The investigators concluded that further studies are needed to better understand the mechanisms and sex differences in chronic rhinosinusitis.

Read more: JAMA Otolaryngology-Head & Neck Surgery

The article presented here is intended to inform you about the broader media perspective on dentistry, regardless of its alignment with the ADA's stance. It is important to note that publication of an article does not imply the ADA's endorsement, agreement, or promotion of its content.