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Relationship between overweight, obesity in younger female patients and cerebrovascular disease

The risk of early-onset ischemic cerebrovascular disease may be increased in adolescent and early adult female patients who are overweight, according to a study published in Stroke.

In the prospective cohort study, investigators analyzed the cerebrovascular outcomes of 10,491 male and female patients aged 14 to 31 years. They followed the patients through the age of 54 years and identified 452 cases of cerebrovascular disease.

Compared with female patients who had a normal weight, those aged 14 and 31 years who were overweight or obese had a higher risk of developing cerebrovascular disease. Similar correlations between overweight and obesity and cerebrovascular disease were not found among male patients. For instance, female patients aged 14 years who were overweight were 2.09 times more likely to develop any cerebrovascular disease compared with male patients of the same age, and female patients aged 31 years were 6.96 times more likely to develop ischemic cerebrovascular disease compared with male patients of the same age.

“The association between childhood overweight and adult cerebrovascular disease is independent of overweight or obesity in adulthood, highlighting the importance for children to achieve and maintain healthy weights,” concluded the study authors.

Read more: Practice Update

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