Review explores silver diamine fluoride in carious enamel remineralization

Investigators evaluated the remineralizing effect of silver diamine fluoride in teeth with dental caries.

In a systematic review published in The Journal of the American Dental Association, the investigators used the PubMed, Scopus and Embase databases to identify 29 in vitro studies, randomized clinical trials and combined in vivo and in vitro studies evaluating the efficacy of 38% silver diamine fluoride in remineralizing primary and young permanent teeth with carious enamel and dentin.

Although the investigators found that silver diamine fluoride was effective in remineralizing the teeth — and in comparison with fluoride gel, casein phosphopeptide-amorphous calcium phosphate, peptides and glass ionomer cement — they noted a high risk of bias among the in vitro studies.

Further, high-quality randomized clinical trials will be needed to determine appropriate concentrations and application times for silver diamine fluoride in this patient population.

Read more: JADA

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