Targeting periodontitis, coronary artery disease

Two novel biomarkers may help assess disease progression in patients with periodontitis and coronary artery disease.

In a study published in Special Care in Dentistry, researchers collected unstimulated saliva samples to analyze the levels of two proteins — vitronectin and fetuin-A — in 60 patients who had both periodontitis and coronary artery disease, had periodontitis or were periodontally and systemically healthy.

The researchers discovered that vitronectin and fetuin-A levels were elevated in the patients with periodontitis and coronary artery disease; however, the proteins declined following scaling and root planing. They also noted that the patients who had periodontitis and coronary artery disease tended to be older, have a higher weight and body mass index as well as have a lower income.

The researchers hope their findings can support the use of the novel biomarkers in patients with periodontitis and coronary artery disease.

Read more: Special Care in Dentistry

The article presented here is intended to inform you about the broader media perspective on dentistry, regardless of its alignment with the ADA's stance. It is important to note that publication of an article does not imply the ADA's endorsement, agreement, or promotion of its content.