What causes sensitive teeth?

Investigators may have uncovered ion channels that play a role in dentine hypersensitivity.

In a study published in the Journal of Dentistry, the investigators conducted a comprehensive literature review to identify ion channels involved in dentine hypersensitivity. They then examined the stimuli responsiveness, physiological roles and pain-related contributions of transient receptor potential channels, Piezo channels and acid-sensing ion channels.

The investigators found that all three ion channels responded to pressure, heat, chemical irritants and acidic environments — potentially resulting in the sensation of pain. They noted that pain signals were generated following the activation of odontoblastic ion channels and subsequent release of compounds that bind to sensory neuron receptors.

Despite the findings, the investigators emphasized that the widespread physiological function of the ion channels identified in the study could present challenges in targeting these pathways. As a result, current standards treatments for managing of dentine sensitivity may continue to be safer and more effective.

Read more: Journal of Dentistry

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